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PTCE Order Entry and Processing Practice Test

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25 practice questions

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  1. Question 1 of 25Easy

    A prescription reads: "Amoxicillin 500 mg, 1 cap po tid pc." Which of the following best describes the dosing instructions?

    1. A. Take one capsule by mouth twice daily before meals.
    2. B. Take one capsule by mouth twice daily after meals.
    3. C. Take one capsule by mouth three times daily before meals.
    4. D. Take one capsule by mouth three times daily after meals.

    Show answer to question 1

    Answer: D. Take one capsule by mouth three times daily after meals.

    "po" means by mouth, "tid" means three times daily, and "pc" means after meals. Therefore, the correct interpretation is take one capsule by mouth three times daily after meals.

    Why the other options are wrong

    • A"bid" would indicate twice daily, and "ac" would indicate before meals, not "tid" and "pc".
    • B"bid" is twice daily, not three times daily as indicated by "tid".
    • C"pc" means after meals, not before; "ac" is before meals.
  2. Question 2 of 25Medium

    A child weighs 44 lbs. The doctor orders a medication at 5 mg/kg. The available concentration is 10 mg/mL. How many mL should be given?

    1. A. 15
    2. B. 20
    3. C. 10
    4. D. 5

    Show answer to question 2

    Answer: C. 10

    Convert weight: 44 lbs ÷ 2.2 = 20 kg. Dose = 20 kg × 5 mg/kg = 100 mg. Volume = 100 mg ÷ 10 mg/mL = 10 mL.

    Why the other options are wrong

    • A15 mL would result from using 30 kg or a miscalculation.
    • B20 mL would result from not converting pounds to kilograms (using 44 kg).
    • D5 mL would result from using 10 kg (half the correct weight).
  3. Question 3 of 25Easy

    A patient weighs 110 lb. What is their weight in kilograms? (Round to one decimal place.)

    1. A. 45.0 kg
    2. B. 50.0 kg
    3. C. 55.0 kg
    4. D. 60.0 kg

    Show answer to question 3

    Answer: B. 50.0 kg

    To convert pounds to kilograms, divide by 2.2 (since 1 kg = 2.2 lb). 110 lb ÷ 2.2 = 50.0 kg.

    Why the other options are wrong

    • A45.0 kg results from dividing by approximately 2.44, an incorrect conversion factor.
    • C55.0 kg results from multiplying by 0.5 instead of dividing by 2.2.
    • D60.0 kg results from dividing by approximately 1.83, an incorrect conversion factor.
  4. Question 4 of 25Medium

    A prescription for phenobarbital is 1.5 grains. The pharmacy has 30 mg tablets. How many tablets should be given? (1 grain = 60 mg)

    1. A. 3 tablets
    2. B. 4 tablets
    3. C. 1 tablet
    4. D. 2 tablets

    Show answer to question 4

    Answer: A. 3 tablets

    Convert grains to mg: 1.5 grains × 60 mg/grain = 90 mg. Then 90 mg ÷ 30 mg/tablet = 3 tablets.

    Why the other options are wrong

    • B4 tablets would be 120 mg, which equals 2 grains, not 1.5 grains.
    • C1 tablet would be 30 mg, which equals 0.5 grain, not 1.5 grains.
    • D2 tablets would be 60 mg, which equals 1 grain, not 1.5 grains.
  5. Question 5 of 25Medium

    A prescription for hydrocodone/APAP 5-325 mg reads: 'Take 1 tablet by mouth every 4 hours as needed for pain.' The pharmacy dispenses 90 tablets. What is the maximum days' supply if the patient uses the medication as directed?

    1. A. 15 days
    2. B. 90 days
    3. C. 45 days
    4. D. 30 days

    Show answer to question 5

    Answer: A. 15 days

    For an as-needed prescription, days' supply uses the maximum daily use. Every 4 hours allows 24 ÷ 4 = 6 tablets per day, so 90 ÷ 6 = 15 days.

    Why the other options are wrong

    • B90 days assumes only 1 tablet per day.
    • C45 days assumes 2 tablets per day.
    • D30 days assumes 3 tablets per day.
  6. Question 6 of 25Easy

    A pediatric patient weighs 22 lb. The physician orders acetaminophen 15 mg/kg/dose. What is the single dose in mg? (1 kg = 2.2 lb)

    1. A. 330 mg
    2. B. 75 mg
    3. C. 150 mg
    4. D. 300 mg

    Show answer to question 6

    Answer: C. 150 mg

    Convert weight to kg: 22 lb ÷ 2.2 = 10 kg. Dose = 15 mg/kg × 10 kg = 150 mg.

    Why the other options are wrong

    • A330 mg results from using 22 lb as kg and multiplying by 15 (22×15=330).
    • B75 mg results from using 5 kg (incorrect conversion: 22÷4.4=5) times 15 mg/kg.
    • D300 mg results from using 20 kg (incorrect conversion: 22×0.9≈20) times 15 mg/kg.
  7. Question 7 of 25Hard

    An adult patient weighing 132 lb is ordered to receive a dopamine infusion at a rate of 5 mcg/kg/min. The IV solution contains dopamine 400 mg in 500 mL of D5W. At what rate, in milliliters per hour, should the infusion pump be programmed?

    1. A. 0.38 mL/hr
    2. B. 22.5 mL/hr
    3. C. 49.5 mL/hr
    4. D. 11.3 mL/hr

    Show answer to question 7

    Answer: B. 22.5 mL/hr

    The patient weighs 60 kg (132 lb / 2.2). The required dose is 300 mcg/min (60 kg x 5 mcg/kg/min), which equals 18,000 mcg/hr (300 mcg/min x 60 min/hr) or 18 mg/hr. The IV bag concentration is 0.8 mg/mL (400 mg / 500 mL), so dividing 18 mg/hr by 0.8 mg/mL gives an infusion rate of 22.5 mL/hr. The distractor 49.5 mL/hr occurs when the patient's weight in pounds is used directly instead of converting to kilograms, while 0.38 mL/hr results from forgetting to convert minutes to hours.

  8. Question 8 of 25Medium

    When repackaging a solid oral dosage form into unit-dose packaging, which of the following must be included on the label in addition to the drug name and strength?

    1. A. Manufacturer name and wholesale price
    2. B. Storage temperature and barcode
    3. C. NDC number, lot number, and expiration date
    4. D. Prescription number and patient name

    Show answer to question 8

    Answer: C. NDC number, lot number, and expiration date

    Repackaged unit-dose labels must include the drug name, strength, NDC number, lot number, and expiration date. Additional information such as the pharmacy name and address may also be required, but the NDC, lot, and expiration are essential for traceability and safety.

    Why the other options are wrong

    • AIncorrect because the manufacturer name is not required on repackaged unit-dose labels, and wholesale price is never included on patient labels.
    • BIncorrect because storage temperature and barcode are not mandatory for repackaged unit-dose labels, though a barcode may be used for inventory management.
    • DIncorrect because prescription number and patient name are typically on the original prescription label, not on repackaged unit-dose labels intended for stock or multi-patient use.
  9. Question 9 of 25Hard

    An IV of 1000 mL is to infuse over 8 hours. The drop factor is 15 gtt/mL. What is the flow rate in drops per minute? (Round to the nearest whole drop.)

    1. A. 21 gtt/min
    2. B. 51 gtt/min
    3. C. 41 gtt/min
    4. D. 31 gtt/min

    Show answer to question 9

    Answer: D. 31 gtt/min

    First, find mL/hr: 1000 mL ÷ 8 hr = 125 mL/hr. Then convert to gtt/min: (125 mL/hr × 15 gtt/mL) ÷ 60 min/hr = 1875 ÷ 60 = 31.25, rounded to 31 gtt/min.

    Why the other options are wrong

    • A21 gtt/min results from dividing 125 by 6 (instead of using drop factor and 60).
    • B51 gtt/min results from dividing 1875 by 36 (incorrect time conversion).
    • C41 gtt/min results from dividing 1875 by 45 (incorrect time conversion).
  10. Question 10 of 25Medium

    A medication has the NDC 12345-6789-01. Which segment of this NDC represents the package size?

    1. A. 6789
    2. B. All three segments together
    3. C. 01
    4. D. 12345

    Show answer to question 10

    Answer: C. 01

    The NDC (National Drug Code) is a three-segment number: labeler code (first 4-5 digits), product code (next 3-4 digits), and package code (last 1-2 digits). The last segment '01' indicates the package size or type.

    Why the other options are wrong

    • AThis is the product code, identifying the specific drug, strength, and dosage form.
    • BEach segment has a distinct meaning; the package size is specifically the last segment.
    • DThis is the labeler code, identifying the manufacturer or repackager.
  11. Question 11 of 25Hard

    A pharmacist reconstitutes a dry powder oral antibiotic with a manufacturer's stability of 10 days at room temperature. The original expiration date on the powder is December 31, 2026. The powder is reconstituted on December 20, 2026. What is the beyond-use date (BUD) for the reconstituted suspension?

    1. A. December 20, 2026
    2. B. January 9, 2027
    3. C. December 30, 2026
    4. D. December 31, 2026

    Show answer to question 11

    Answer: C. December 30, 2026

    The beyond-use date for a reconstituted product is based on the manufacturer's stability data, not the original expiration date. Since the stability is 10 days at room temperature, and reconstitution is on December 20, the BUD is 10 days later, December 30, 2026. The original expiration (Dec 31) is later, so it does not limit the BUD.

    Why the other options are wrong

    • ADecember 20 is the date of reconstitution, not the beyond-use date.
    • BJanuary 9 would be 20 days after reconstitution, which exceeds the 10-day stability.
    • DDecember 31 is the original expiration of the powder, but the reconstituted product has a shorter stability of 10 days from reconstitution.
  12. Question 12 of 25Easy

    A prescription reads: 'Take 1 tablet by mouth twice daily.' The pharmacist dispenses 30 tablets. How many days will this supply last?

    1. A. 60 days
    2. B. 15 days
    3. C. 30 days
    4. D. 7.5 days

    Show answer to question 12

    Answer: B. 15 days

    The patient takes 2 tablets per day (1 tablet × 2 doses). Days supply = total tablets ÷ tablets per day = 30 ÷ 2 = 15 days.

    Why the other options are wrong

    • AThis would require taking 0.5 tablets per day, which is not the case.
    • CThis would be correct only if the patient took 1 tablet per day, but the sig says twice daily.
    • DThis would be correct if the patient took 4 tablets per day, but the sig is twice daily.
  13. Question 13 of 25Medium

    A pharmacist needs to prepare 200 mL of a 1:4000 (w/v) potassium permanganate solution from a 1:500 stock. How many milliliters of the stock solution are required?

    1. A. 25 mL
    2. B. 50 mL
    3. C. 12.5 mL
    4. D. 40 mL

    Show answer to question 13

    Answer: A. 25 mL

    C1 = 1/500 = 0.002, V1 = ?, C2 = 1/4000 = 0.00025, V2 = 200 mL. C1V1 = C2V2 → 0.002 × V1 = 0.00025 × 200 → V1 = (0.05)/0.002 = 25 mL.

    Why the other options are wrong

    • B50 mL would be for a 1:2000 dilution.
    • C12.5 mL would be for a 1:8000 dilution.
    • D40 mL would give a higher concentration than desired.
  14. Question 14 of 25Medium

    A pharmacy technician is processing a return of an expired Schedule II controlled substance to the wholesaler for credit. Which DEA form is required for this transaction?

    1. A. DEA Form 222
    2. B. DEA Form 106
    3. C. DEA Form 224
    4. D. DEA Form 41

    Show answer to question 14

    Answer: A. DEA Form 222

    DEA Form 222 is required for the transfer of Schedule II controlled substances between registrants, such as returning expired CII drugs to a wholesaler. The form must be used with the appropriate notation for returns.

    Why the other options are wrong

    • BDEA Form 106 is used to report theft or loss of controlled substances.
    • CDEA Form 224 is the application for retail pharmacy registration, not for returns.
    • DDEA Form 41 is used for reporting destruction of controlled substances, not for returning them to a wholesaler.
  15. Question 15 of 25Medium

    A patient weighs 70 kg. What is their weight in pounds? (1 kg = 2.2 lb)

    1. A. 140 lb
    2. B. 165 lb
    3. C. 175 lb
    4. D. 154 lb

    Show answer to question 15

    Answer: D. 154 lb

    Multiply kilograms by 2.2 lb/kg: 70 kg × 2.2 lb/kg = 154 lb.

    Why the other options are wrong

    • A140 lb results from multiplying by 2, not 2.2.
    • B165 lb results from multiplying by 2.357, an incorrect factor.
    • C175 lb results from multiplying by 2.5, an incorrect factor.
  16. Question 16 of 25Hard

    A patient weighing 176 lb is to receive dopamine at 5 mcg/kg/min. The available solution is 400 mg of dopamine in 250 mL of D5W. The IV set delivers 60 gtt/mL. What is the drip rate in drops per minute?

    1. A. 15 gtt/min
    2. B. 60 gtt/min
    3. C. 30 gtt/min
    4. D. 45 gtt/min

    Show answer to question 16

    Answer: A. 15 gtt/min

    Convert weight: 176 lb ÷ 2.2 = 80 kg. Dose per minute: 5 mcg/kg/min × 80 kg = 400 mcg/min = 0.4 mg/min. Concentration: 400 mg/250 mL = 1.6 mg/mL. Volume per minute: 0.4 mg ÷ 1.6 mg/mL = 0.25 mL/min. Drip rate: 0.25 mL/min × 60 gtt/mL = 15 gtt/min.

    Why the other options are wrong

    • B60 gtt/min would result from a dose of 20 mcg/kg/min (1600 mcg/min) or from using 1 mL/min.
    • C30 gtt/min would result from a dose of 10 mcg/kg/min (800 mcg/min) or from using 0.5 mL/min.
    • D45 gtt/min would result from a dose of 7.5 mcg/kg/min (600 mcg/min) or from using 0.75 mL/min.
  17. Question 17 of 25Medium

    Which of the following is NOT required on a prescription label for a non-controlled medication?

    1. A. Patient's name
    2. B. Patient's social security number
    3. C. Directions for use
    4. D. Drug name and strength

    Show answer to question 17

    Answer: B. Patient's social security number

    Federal and state regulations require the patient's name, drug name and strength, and directions for use on a prescription label. The patient's social security number is not a required element and should not be included for privacy reasons.

    Why the other options are wrong

    • APatient's name is a required element on all prescription labels.
    • CDirections for use are required so the patient knows how to take the medication.
    • DDrug name and strength are required to identify the medication.
  18. Question 18 of 25Hard

    How many milliliters of a 95% (v/v) ethanol solution are needed to prepare 600 mL of a 70% (v/v) solution?

    1. A. 632 mL
    2. B. 380 mL
    3. C. 442 mL
    4. D. 525 mL

    Show answer to question 18

    Answer: C. 442 mL

    C1V1 = C2V2 → 95 × V1 = 70 × 600 → V1 = (70 × 600)/95 = 42000/95 ≈ 442.1 mL, rounded to 442 mL.

    Why the other options are wrong

    • A632 mL would require a lower concentration stock.
    • B380 mL would correspond to a 60% final concentration.
    • D525 mL would give about 83% final concentration.
  19. Question 19 of 25Easy

    A patient is to receive 500 mL of a 0.9% sodium chloride (NaCl) solution. How many grams of NaCl are contained in this solution?

    1. A. 45 g
    2. B. 4.5 g
    3. C. 0.9 g
    4. D. 9 g

    Show answer to question 19

    Answer: B. 4.5 g

    0.9% w/v means 0.9 g of NaCl per 100 mL of solution. Therefore, in 500 mL: (0.9 g/100 mL) × 500 mL = 4.5 g.

    Why the other options are wrong

    • A45 g would be from 9% concentration, not 0.9%.
    • C0.9 g is the amount in 100 mL, not in 500 mL.
    • D9 g is the amount in 1000 mL (1 L) of 0.9% solution.
  20. Question 20 of 25Easy

    A patient is to receive 1000 mL of normal saline over 8 hours. What is the flow rate in mL per hour?

    1. A. 150 mL/hr
    2. B. 125 mL/hr
    3. C. 100 mL/hr
    4. D. 80 mL/hr

    Show answer to question 20

    Answer: B. 125 mL/hr

    Flow rate (mL/hr) = Total volume (mL) ÷ Time (hours) = 1000 mL ÷ 8 hr = 125 mL/hr.

    Why the other options are wrong

    • A150 mL/hr would deliver 1200 mL in 8 hours, exceeding the prescribed volume.
    • C100 mL/hr would be 800 mL in 8 hours, not 1000 mL.
    • D80 mL/hr would deliver only 640 mL in 8 hours, insufficient volume.
  21. Question 21 of 25Easy

    A patient's temperature is 98.6°F. What is it in Celsius?

    1. A. 37.0°C
    2. B. 38.0°C
    3. C. 36.0°C
    4. D. 39.0°C

    Show answer to question 21

    Answer: A. 37.0°C

    Use the formula (°F - 32) × 5/9 = °C. (98.6 - 32) = 66.6; 66.6 × 5/9 = 37.0°C.

    Why the other options are wrong

    • B38.0°C results from using the reverse formula (multiply by 9/5 and add 32).
    • C36.0°C results from only subtracting 32 without multiplying by 5/9.
    • D39.0°C results from adding 32 instead of subtracting.
  22. Question 22 of 25Hard

    A prescription reads: 'Take 1 tab po qid x 10d.' What is the correct interpretation of this sig code?

    1. A. Take one tablet by mouth every 4 hours for 10 days
    2. B. Take one tablet by mouth once daily for 10 days
    3. C. Take one tablet by mouth four times a day for 10 days
    4. D. Take one tablet by mouth three times a day for 10 days

    Show answer to question 22

    Answer: C. Take one tablet by mouth four times a day for 10 days

    In standard sig codes, 'po' means by mouth, 'qid' means four times a day (quater in die), and 'x 10d' means for 10 days. 'q4h' would mean every 4 hours, 'qd' means once daily, and 'tid' means three times a day.

    Why the other options are wrong

    • AEvery 4 hours is abbreviated as q4h, not qid; qid implies four times daily at evenly spaced intervals but not strictly every 4 hours.
    • BOnce daily is abbreviated as qd or daily, not qid.
    • DThree times a day is abbreviated as tid, not qid.
  23. Question 23 of 25Medium

    A medication administration record shows a dose scheduled at 1430 hours. What is this time in standard AM/PM format?

    1. A. 2:30 AM
    2. B. 3:30 PM
    3. C. 1:30 PM
    4. D. 2:30 PM

    Show answer to question 23

    Answer: D. 2:30 PM

    Military time 1430 is 14:30. Subtract 12 from hours (14 - 12 = 2) and add PM: 2:30 PM.

    Why the other options are wrong

    • A2:30 AM would be 0230 hours.
    • B3:30 PM would be 1530 hours.
    • C1:30 PM would be 1330 hours.
  24. Question 24 of 25Medium

    A patient is to receive 5 grains of aspirin. How many milligrams is that? (1 gr = 60 mg)

    1. A. 250 mg
    2. B. 350 mg
    3. C. 400 mg
    4. D. 300 mg

    Show answer to question 24

    Answer: D. 300 mg

    Multiply grains by 60 mg/gr: 5 gr × 60 mg/gr = 300 mg.

    Why the other options are wrong

    • A250 mg results from using 50 mg/gr, an incorrect conversion factor.
    • B350 mg results from using 70 mg/gr, an incorrect conversion factor.
    • C400 mg results from using 80 mg/gr, an incorrect conversion factor.
  25. Question 25 of 25Hard

    A vial contains 2 g of amoxicillin powder for oral suspension. Reconstitution with 50 mL of water yields a concentration of 250 mg per 5 mL. If a patient needs a dose of 150 mg, how many milliliters should be administered?

    1. A. 3 mL
    2. B. 4 mL
    3. C. 5 mL
    4. D. 2.5 mL

    Show answer to question 25

    Answer: A. 3 mL

    Concentration: 250 mg/5 mL = 50 mg/mL. For 150 mg dose: volume = 150 mg / 50 mg/mL = 3 mL.

    Why the other options are wrong

    • B4 mL provides 200 mg.
    • C5 mL provides 250 mg.
    • D2.5 mL would provide 125 mg (since 250 mg/5 mL = 50 mg/mL × 2.5 mL = 125 mg).

The full PTCE bank has 869 Order Entry and Processing questions. See plans

Order Entry and Processing is 22.5% of the PTCE content outline that PTCB uses from January 6, 2026. Below are 25 original Order Entry and Processing practice questions, each with the answer and an explanation.

Source: PTCB PTCE content outline (January 2026).

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Questions, answered

Are these actual PTCE questions?

No. They are original practice questions written from the public exam outline, not questions taken from the exam. Exam owners keep live questions confidential.

How much of the PTCE is Order Entry and Processing?

22.5% of the exam content, under the PTCB content outline used from January 6, 2026. The PTCE has 90 questions (80 scored) in 1 hour 50 minutes. Source: PTCB PTCE content outline (January 2026).

Is this PTCE Order Entry and Processing practice test free?

Yes. The 25 questions on this page, with answers and explanations, are free to use, and there is no sign up. The full PTCE bank of 3,277 questions, with timed section tests and an AI tutor, comes with a plan.

How should I use this practice test?

Answer each question before you open Show answer, then read why the correct option is right and the others are not. Note the topics you miss and review them first. The PTCE study guide has 8 lessons for Order Entry and Processing, listed on this page.

These are original practice questions written from the public exam outline. They are not actual exam questions. PTCE and PTCB are trademarks of their owner. tests.global is not affiliated with or endorsed by PTCB.

Updated November 1, 2026.