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CCRN · Respiratory · 8 min read

Airway Management, Intubation and Tracheostomy

In this lesson you will
  • Differentiate between alterations in airway resistance and lung compliance, utilizing continuous waveform capnography and clinical assessment to confirm and monitor artificial airway placement.
  • Execute safe nursing management of endotracheal tubes and tracheostomies, including cuff pressure regulation, suctioning techniques, and immediate response to accidental decannulation.
  • Recognize acute, life-threatening airway emergencies, such as tracheoinnominate artery fistula, acute cannula obstruction, and procedural complications like methemoglobinemia, and implement rapid, protocol-driven interventions within the AACN Synergy Model.

Acute Airway Assessment, Rapid Sequence Intubation, and Placement Confirmation

Caring for unstable patients requires vigilant physical assessment to identify upper airway compromise before full obstruction occurs. Inspiratory stridor serves as a hallmark sign of upper airway narrowing and demands an immediate clinical evaluation for impending respiratory failure. Rapidly evolving presentations, such as angioedema with acute swelling of the lips, tongue, and pharynx, require early preparation for definitive airway control before the passage is completely occluded. When managing a patient with a suspected cervical spine injury, the critical care team must maintain manual in-line stabilization throughout all airway maneuvers and intubation efforts while keeping the primary focus on oxygenation and airway rescue.

Rapid sequence intubation (RSI) is frequently utilized in the critical care setting to secure the airway promptly. This process involves thorough preoxygenation followed by the administration of an induction agent and a neuromuscular blockade. Although classical approaches minimized positive-pressure ventilation before securing the tube, bag-mask ventilation may be provided when needed to prevent hypoxemia according to the airway team's plan. Video laryngoscopy provides an indirect, camera-assisted view of the glottis that may improve first-pass intubation success, particularly in patients with difficult airways. Notably, cricoid pressure is no longer routinely recommended during rapid sequence intubation because it does not reliably prevent aspiration and can significantly worsen the clinician's laryngoscopic view.

Immediately following intubation, the critical care registered nurse participates in verifying tube placement. Continuous waveform capnography is the gold standard to confirm initial endotracheal tube placement and continuously monitor tube position. Disposable colorimetric end-tidal carbon dioxide detectors provide qualitative verification by changing from purple to yellow in the presence of exhaled carbon dioxide. However, clinicians must recognize that severe low cardiac output states or cardiac arrest can cause false-negative capnography readings due to inadequate pulmonary blood flow delivering carbon dioxide to the lungs. A sudden loss of the end-tidal carbon dioxide waveform during mechanical ventilation mandates an immediate assessment for tube displacement, tube obstruction, circuit or monitor disconnection, or catastrophic circulatory collapse.

Immediate physical assessment must accompany capnography. The nurse performs bilateral auscultation of breath sounds in the midaxillary lines and auscultates over the epigastrium. Hearing epigastric gurgling during ventilation raises immediate concern for esophageal intubation; the nurse must promptly assess waveform capnography, alert the airway team, and support oxygenation while tube placement is urgently evaluated. A portable chest radiograph confirms endotracheal tube depth, with the optimal position of the tube tip located 3 to 5 centimeters above the carina on a neutral-neck image. However, a chest radiograph cannot reliably rule out esophageal intubation compared to capnography.

Exam tip. Waveform capnography is always the gold standard for verifying endotracheal placement. Never rely on a portable chest radiograph to rule out esophageal intubation, and remember that profound shock or cardiac arrest can produce a false-negative capnography reading due to lack of pulmonary perfusion.

Common mistakes

  • Instilling normal saline into an endotracheal tube to loosen secretions, which does not reliably thin secretions and can worsen patient oxygenation.
  • Attempting blind reinsertion of a tracheostomy tube after accidental decannulation in a fresh stoma less than 7 to 10 days old, which risks catastrophic false tract formation.
  • Placing a one-way speaking valve onto a tracheostomy tube without completely deflating the cuff, which causes total airway occlusion and patient asphyxiation.
  • Relying solely on pulse oximetry during bronchoscopy or recovery can miss hypoventilation; monitor exhaled carbon dioxide when feasible and obtain a blood gas when accurate assessment of PaCO2 is needed.

Key points

  • Continuous waveform capnography is the gold standard for verifying and monitoring endotracheal tube placement; colorimetric devices turn from purple to yellow with exhaled CO2, but severe low cardiac output states can cause false negatives.
  • A neutral-neck chest radiograph confirms tube depth (optimally 3 to 5 cm above the carina) but cannot rule out esophageal intubation; head flexion pushes the tube toward the carina, while extension risks extubation.
  • Maintain endotracheal and tracheostomy cuff pressures between 20 and 30 cm H2O to balance mucosal capillary perfusion against the risks of aspiration and air leak.
  • Elevated peak pressure with a normal plateau pressure suggests increased airflow resistance; elevations in both pressures warrant assessment for reduced respiratory-system compliance, increased PEEP or auto-PEEP, and ventilator-setting changes.
  • Keep an obturator and same-size and smaller spare tubes at the bedside; after decannulation of an immature tracheostomy, summon emergency airway assistance, avoid blind reinsertion, and ventilate over the mouth while occluding the stoma only if the upper airway is patent.
  • Tracheoinnominate artery fistula presents as sentinel or massive bleeding, managed emergently by hyperinflating the cuff or applying digital compression through the stoma against the posterior sternum while summoning help.
  • Topical benzocaine spray can cause acquired methemoglobinemia (dark blood, cyanosis, SpO2 around 85% with normal PaO2), requiring co-oximetry confirmation and provider-prescribed intravenous methylene blue.

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Original lesson written for CCRN practice · updated October 31, 2026. Exam names are trademarks of their owners; tests.global is not affiliated with them.