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CCRN · Professional Caring and Ethical Practice · 7 min read

DNR, Withdrawing Treatment and Goals of Care

In this lesson you will
  • Differentiate the clinical and legal boundaries of code status orders, including Do Not Resuscitate (DNR) and Allow Natural Death (AND), from broader goals of care.
  • Formulate an evidence-based nursing plan for withdrawing life-sustaining therapies, prioritizing comfort medication titration, device management, and symptom control.
  • Apply foundational ethical principles, advance directives, and the AACN Synergy Model competency of Advocacy and Moral Agency to resolve clinical conflicts and mitigate moral distress.

Code Status Clarification and Goals of Care

In the critical care setting, clear communication regarding resuscitation preferences is foundational. A Do Not Resuscitate (DNR) order specifically directs clinicians not to perform cardiopulmonary resuscitation (CPR) during a cardiac arrest. This limitation includes chest compressions, resuscitative defibrillation, and airway interventions undertaken as part of CPR. However, a DNR order does not restrict intensive medical interventions, such as vasoactive infusions, blood products, or renal replacement therapy, prior to an actual arrest unless explicitly stated. Clinicians must recognize that limitations on intubation for acute respiratory failure prior to cardiac arrest require separate clarification. Allow Natural Death (AND) is an alternative term for a DNR order that emphasizes a natural dying process, but it does not by itself establish a comfort-only plan of care.

Establishing code status is an ongoing clinical responsibility. The critical care team should clarify code status and goals of care upon admission and revisit them whenever the patient's condition, prognosis, or preferences change significantly. If no applicable resuscitation-limiting order or legally recognized patient or surrogate instruction is in place, the critical care team must initiate resuscitation while promptly clarifying the patient's wishes under applicable law and policy. Code status is also not static across clinical transitions; before a procedure requiring anesthesia, an existing DNR order must undergo required reconsideration with the patient or authorized surrogate rather than being automatically suspended.

Goals of care conversations frequently address treatments that clinicians find ethically challenging. Critical care consensus favors the term 'potentially inappropriate treatment' when an intervention may achieve an intended physiological effect, but clinicians question whether providing it is ethically appropriate due to competing ethical considerations. In contrast, 'physiologically futile treatment' refers specifically to an intervention that cannot achieve its intended physiological goal. Differentiating these concepts helps teams navigate complex decisions without mischaracterizing clinical realities.

Comparison of Resuscitation Orders and Treatment Concepts
Term / OrderClinical Scope and InterventionsKey Clinical Considerations
Do Not Resuscitate (DNR) / Allow Natural Death (AND)Withholds CPR, chest compressions, defibrillation, and CPR-related airway interventions during cardiac arrest.Does not restrict pre-arrest interventions (vasopressors, blood, dialysis) unless explicitly ordered; requires separate clarification for pre-arrest intubation.
Potentially Inappropriate TreatmentInterventions that can achieve an intended physiological effect.Clinicians judge that competing ethical considerations may justify not providing the therapy.
Physiologically Futile TreatmentInterventions that cannot achieve their intended physiological goal.The therapy has no capacity to produce the desired physiological outcome.
Exam tip. Do not equate a DNR order with 'comfort care only' or 'do not treat.' A patient who is DNR can still receive maximum intensive support, including rapid titration of vasopressors, continuous renal replacement therapy, and blood transfusions, until an actual cardiac arrest occurs.

Common mistakes

  • Assuming a Do Not Resuscitate order implies 'do not treat,' leading to the inappropriate withholding or down-titration of active critical care interventions (e.g., vasopressors, inotropes, or blood products) prior to a cardiac arrest.
  • During withdrawal of mechanical ventilation, avoid ongoing neuromuscular blockade when feasible because it masks behavioral signs of pain and respiratory distress; if paralysis persists, provide anticipatory comfort medication and use available indicators to assess the patient.
  • Using respiratory rate as the sole indicator of patient comfort during terminal weaning or extubation, which can lead to inadequate opioid titration for the subjective sensation of dyspnea.
  • Conflating clinical decision-making capacity with legal competence, or applying the best-interests standard before attempting substituted judgment based on the patient's known values.

Key points

  • A DNR order exclusively directs clinicians to withhold CPR during cardiac arrest; it does not restrict pre-arrest critical care therapies, and intubation limits require distinct clarification.
  • Withholding and withdrawing life-sustaining therapy are ethically and legally equivalent, and starting an intensive trial does not mandate its indefinite continuation.
  • Before withdrawing mechanical ventilation, confirm that neuromuscular blockade has worn off or been reversed so it does not mask behavioral signs of distress.
  • Within orders or protocols, titrate opioids for pain and dyspnea and use benzodiazepines when indicated for anxiety or refractory agitation; titration should be proportionate to assessed symptoms, with the principle of double effect relevant when a harmful effect is foreseeable.
  • Electronic cardiac devices require proactive discussion: offer deactivation of ICD shocks in accordance with the patient's or authorized surrogate's wishes, appropriate orders, and policy, while considering pacemaker pacing separately based on goals and device dependence.
  • The AACN Synergy Model highlights Advocacy and Moral Agency as vital for resolving goals-of-care conflicts, mitigating moral distress, and integrating early palliative care concurrently with curative therapies.
  • Care withdrawal decisions must remain separate from organ donation processes, though timely referral to the organ procurement organization must occur per policy.

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Original lesson written for CCRN practice · updated October 14, 2026. Exam names are trademarks of their owners; tests.global is not affiliated with them.