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HESI A2 Reading Practice Test

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25 practice questions

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  1. Question 1 of 25Medium

    Passage: 'The prevalence of diabetes has increased dramatically over the past two decades, driven largely by lifestyle factors and an aging population. However, early detection and management can significantly reduce complications. Public health campaigns have focused on promoting regular screenings, especially among high-risk groups.' What is the main idea of the passage?

    1. A. Screenings are unnecessary for low-risk groups.
    2. B. Aging population is the sole driver of diabetes increase.
    3. C. Lifestyle choices are the only cause of diabetes.
    4. D. Diabetes is increasing but manageable with early detection.

    Show answer to question 1

    Answer: D. Diabetes is increasing but manageable with early detection.

    The passage first states the increase, then emphasizes that early detection and management reduce complications, and mentions screenings. The main idea combines the rise with the positive aspect of management.

    Why the other options are wrong

    • AThe passage does not claim screenings are unnecessary for any group.
    • BThe passage lists both lifestyle and aging, not aging alone.
    • CThe passage says 'largely' not 'only', so this is an overstatement.
  2. Question 2 of 25Medium

    Read the following passage: 'The human body maintains a stable internal environment through a process called homeostasis. For example, when body temperature rises above normal, the hypothalamus in the brain triggers sweating and vasodilation to cool the body. Once temperature returns to normal, these responses cease. This is an example of negative feedback, where the response counteracts the stimulus. Without such mechanisms, the body would be unable to function properly.' What is the main idea of the passage?

    1. A. Sweating is the primary method of cooling the body.
    2. B. The hypothalamus is responsible for all bodily functions.
    3. C. The body uses negative feedback to maintain homeostasis.
    4. D. Positive feedback is more common than negative feedback.

    Show answer to question 2

    Answer: C. The body uses negative feedback to maintain homeostasis.

    The passage explains homeostasis and uses temperature regulation as an example of negative feedback. The main idea is that negative feedback helps maintain a stable internal environment.

    Why the other options are wrong

    • ASweating is mentioned as one cooling method, but the passage is not focused solely on sweating; it is an example within the larger concept.
    • BThe hypothalamus is involved in temperature regulation, but the passage does not claim it controls all functions.
    • DThe passage describes negative feedback, not positive feedback, and does not compare frequencies.
  3. Question 3 of 25Easy

    Passage

    Urinary tract infections are among the most common bacterial infections encountered in clinical practice. When a patient presents with symptoms such as dysuria and increased urinary frequency, a clean-catch urine specimen is typically obtained. While a rapid dipstick urinalysis can provide immediate clues, such as the presence of leukocyte esterase and nitrites, a definitive diagnosis often requires a laboratory culture. During this process, the urine sample is plated onto specific growth media and incubated to allow any bacteria present to multiply. Identifying the specific organism and determining its antimicrobial susceptibility ensures that the clinician selects the most effective antibiotic regimen.

    As used in the passage, what is the meaning of the word "culture"?

    1. A. The controlled propagation of microorganisms in a growth medium
    2. B. The physical cleansing of diagnostic instruments after clinical use
    3. C. The shared beliefs and social customs of a specific group
    4. D. The refinement of intellectual and artistic tastes through education

    Show answer to question 3

    Answer: A. The controlled propagation of microorganisms in a growth medium

    In this microbiological context, "culture" refers to growing microorganisms in an artificial medium to identify the pathogen causing an infection. While the word commonly denotes shared social beliefs or artistic refinement, those everyday definitions do not fit the laboratory diagnostic process described in the text.

  4. Question 4 of 25Hard

    Passage

    Modern intensive care units are saturated with acoustic monitoring devices, creating a phenomenon known as alarm fatigue. Nurses and medical staff are bombarded with hundreds of sensory alerts per shift, up to ninety percent of which are clinically insignificant or false alarms. Over time, this sensory overload desensitizes clinicians, leading to delayed response times or inadvertently silenced warning systems that can prove fatal for deteriorating patients. To combat this critical safety threat, hospital administrators have begun tailoring alarm parameters to individual patient baselines rather than relying on default factory thresholds. Coupled with smart middleware that filters redundant notifications before they reach the nursing staff, these customized protocols dramatically reduce nuisance noise while ensuring genuine medical emergencies receive prompt clinical intervention.

    Which detail from the passage represents a solution specifically designed to prevent staff from becoming desensitized to clinical alerts?

    1. A. Adjusting monitor parameters to match individual patient baselines.
    2. B. Increasing the acoustic volume of alarms for deteriorating patients.
    3. C. Silencing bedside warning systems during routine nursing tasks.
    4. D. Relying exclusively on default factory alarm thresholds across all units.

    Show answer to question 4

    Answer: A. Adjusting monitor parameters to match individual patient baselines.

    The author explicitly identifies tailoring alarm parameters to individual patient baselines and using filtering middleware as the solutions to nuisance alarms and desensitization. Relying on default factory thresholds is cited as the existing practice that contributed to the problem, making it incorrect. Silencing alarms is described as a dangerous consequence of alarm fatigue rather than an approved clinical remedy.

  5. Question 5 of 25Hard

    Passage

    Cognitive dissonance occurs when a person holds two conflicting beliefs or is confronted with information that contradicts their existing values. This mental discomfort often leads individuals to change their attitudes or justify their behaviors to reduce the tension. For instance, a person who values environmental conservation but continues to drive a gas-heavy vehicle may experience this tension and might justify it by claiming their individual impact is too small to matter.

    Which of the following scenarios best exemplifies the concept of cognitive dissonance as described in the passage?

    1. A. An athlete who follows a strict diet to improve their overall physical performance.
    2. B. A student studies hard because they want to achieve high grades in school.
    3. C. A smoker who knows smoking is harmful but continues the habit to reduce stress.
    4. D. A person feels happy when they successfully complete a difficult task.

    Show answer to question 5

    Answer: C. A smoker who knows smoking is harmful but continues the habit to reduce stress.

    Cognitive dissonance involves the tension between a belief (smoking is harmful) and a behavior (smoking). The other options describe consistent behaviors and beliefs that do not create mental conflict.

  6. Question 6 of 25Easy

    Passage

    The implementation of mandatory physical education in schools has become a point of contention among educators. Proponents argue that scheduled exercise is essential for combating childhood obesity and fostering lifelong healthy habits. They point to rising rates of sedentary lifestyles as a primary reason for the shift in focus toward movement. Conversely, some administrators suggest that the rigid scheduling of physical education detracts from core academic subjects like mathematics and literacy. These critics argue that instructional time is a precious resource that should be prioritized for cognitive development rather than physical activity.

    How do the two viewpoints presented in the passage differ regarding school scheduling?

    1. A. One emphasizes academic achievement while the other focuses on physical health.
    2. B. One supports early graduation while the other supports extended school days.
    3. C. One focuses on student nutrition while the other focuses on student fitness.
    4. D. One promotes mandatory exercise while the other promotes elective programs.

    Show answer to question 6

    Answer: A. One emphasizes academic achievement while the other focuses on physical health.

    The first group of educators prioritizes physical health to combat obesity, whereas the second group prioritizes academic subjects like math and literacy. This reflects the central conflict between physical and cognitive instruction time.

  7. Question 7 of 25Medium

    Passage

    Modern dietary guidelines often emphasize the importance of consuming whole grains to improve digestive health. However, many processed cereals marketed as 'healthy' contain high amounts of refined sugar. While some nutritionists argue that these cereals are a convenient option for busy lifestyles, a more rigorous analysis of nutritional labels suggests that the sugar content often outweighs the benefits of the added fiber.

    What is the author's purpose in mentioning the 'busy lifestyles' of consumers?

    1. A. To provide a neutral perspective on why people choose certain foods.
    2. B. To suggest that busy people should avoid eating breakfast altogether.
    3. C. To argue that convenience is the most important factor in nutrition.
    4. D. To support the claim that processed cereals are beneficial for health.

    Show answer to question 7

    Answer: A. To provide a neutral perspective on why people choose certain foods.

    The author mentions busy lifestyles to acknowledge a common counter-argument or perspective before presenting their own critical view. This provides context for why the cereals are popular despite their nutritional drawbacks.

  8. Question 8 of 25Medium

    Passage

    The use of antibiotics has revolutionized modern medicine by providing an effective way to treat bacterial infections. Before the discovery of penicillin, even minor injuries could lead to fatal infections. However, the widespread misuse and overuse of these drugs have led to the emergence of antibiotic-resistant bacteria. These 'superbugs' are increasingly difficult to treat, posing a significant challenge to global public health and making standard medical procedures more dangerous.

    How is the passage structured?

    1. A. Problem and solution.
    2. B. Comparison and contrast.
    3. C. Chronological order.
    4. D. Cause and effect.

    Show answer to question 8

    Answer: D. Cause and effect.

    The passage explains how the misuse of antibiotics (cause) has led to the development of antibiotic-resistant bacteria (effect). While it mentions the history of medicine, the primary structure is explaining the consequence of drug misuse.

  9. Question 9 of 25Medium

    Passage

    Healthcare-associated infections represent a significant cause of preventable illness and mortality in modern clinical environments. Research consistently demonstrates that pathogens are most commonly transmitted between patients via the contaminated hands of healthcare workers. Despite the availability of alcohol-based hand rubs and strict institutional protocols, compliance rates with hand hygiene guidelines remain stubbornly below optimal benchmarks. Many staff members cite heavy workloads, skin irritation, and lack of time as common barriers to frequent handwashing. Overcoming this challenge requires systemic changes, including accessible sanitizing stations, ongoing staff education, and leadership accountability, to ensure that basic hygiene practices are prioritized during patient care.

    What is the author's primary purpose in the passage?

    1. A. To explain the problem of low hand hygiene compliance and advocate for solutions.
    2. B. To demonstrate that healthcare workers are personally negligent regarding patient safety.
    3. C. To analyze the biological mechanisms that allow pathogens to survive on human skin.
    4. D. To contrast the chemical properties of soap and water with alcohol-based sanitizers.

    Show answer to question 9

    Answer: A. To explain the problem of low hand hygiene compliance and advocate for solutions.

    The author examines why hand hygiene adherence remains suboptimal among clinical staff and proposes systemic remedies to improve compliance. Rather than accusing workers of personal negligence, the passage highlights systemic obstacles such as heavy workloads and limited time.

  10. Question 10 of 25Easy

    Passage

    Prior to changing a sterile wound dressing, a nurse must verify the physician's order and gather all necessary supplies. After assembling the materials, the clinician performs hand hygiene and explains the procedure to the patient. Once the patient is positioned comfortably, the old dressing is carefully removed and discarded in a biohazard receptacle. The nurse inspects the wound bed for signs of infection before donning sterile gloves. Only after sterile gloves are applied does the nurse irrigate the wound and place the new sterile gauze. Finally, the site is secured with medical tape and the procedure is documented in the medical record.

    According to the passage, which action must occur immediately after the nurse inspects the wound bed?

    1. A. Irrigating the wound bed
    2. B. Securing the gauze with tape
    3. C. Removing the old dressing
    4. D. Donning a pair of sterile gloves

    Show answer to question 10

    Answer: D. Donning a pair of sterile gloves

    The passage specifies that the nurse inspects the wound bed before donning sterile gloves, meaning donning sterile gloves occurs immediately after inspection. Irrigating the wound bed is incorrect because that action takes place only after the sterile gloves have been applied.

  11. Question 11 of 25Easy

    Passage

    The Mediterranean diet emphasizes the consumption of plant-based foods, such as fruits, vegetables, legumes, and whole grains. It also prioritizes healthy fats, specifically olive oil, over saturated fats like butter. While seafood and poultry are included in moderation, red meats and sweets are consumed infrequently. Researchers have linked this eating pattern to lower rates of chronic illnesses, including type 2 diabetes and certain types of cancer.

    Which of the following best describes the dietary pattern mentioned?

    1. A. A high-protein diet focused on red meats.
    2. B. A diet centered on plant-based foods and healthy fats.
    3. C. A restrictive diet that excludes all types of fats.
    4. D. A diet primarily consisting of seafood and sweets.

    Show answer to question 11

    Answer: B. A diet centered on plant-based foods and healthy fats.

    The passage explicitly highlights plant-based foods and healthy fats like olive oil as the main components. It notes that red meats and sweets are consumed only infrequently.

  12. Question 12 of 25Medium

    Passage for the next questions

    Plain Language in Patient Education

    Effective patient education is a cornerstone of quality nursing care. When patients understand their health conditions and treatment plans, they are more likely to follow medical advice and achieve better outcomes. One key strategy for improving patient understanding is the use of plain language. Plain language means communicating information in a clear, straightforward manner without unnecessary medical jargon. For example, instead of saying hypertension, a nurse might say high blood pressure. This approach helps patients grasp complex concepts more easily. Research suggests that many patients struggle to understand health information. For instance, a hypothetical survey could indicate that nearly half of patients misunderstand discharge instructions. By using plain language, nurses can reduce confusion and empower patients to take an active role in their care. Additionally, plain language materials can be especially helpful for patients with limited health literacy or those who speak English as a second language. Nurses can apply plain language principles in various ways. They should speak slowly, use short sentences, and define any necessary technical terms. Written materials, such as pamphlets or after visit summaries, should also be written at a reading level appropriate for the average patient. Visual aids, like diagrams or pictures, can further enhance understanding. Ultimately, the goal of plain language is not to oversimplify but to make information accessible. When patients comprehend their health information, they can make informed decisions and follow treatment plans correctly. This leads to better health outcomes and increased patient satisfaction. Therefore, incorporating plain language into patient education is a vital skill for every nurse.

    What is the main idea of the passage?

    1. A. Plain language helps patients understand health information and improves outcomes.
    2. B. Visual aids are more important than spoken words.
    3. C. Nurses should avoid using any medical terms.
    4. D. Patients with low health literacy cannot learn.

    Show answer to question 12

    Answer: A. Plain language helps patients understand health information and improves outcomes.

    The passage discusses how plain language improves patient understanding and outcomes, citing benefits and applications. It emphasizes that plain language makes information accessible, leading to better health outcomes and patient satisfaction.

    Why the other options are wrong

    • BThe passage mentions visual aids as helpful but does not claim they are more important than spoken words.
    • CThe passage says to define necessary technical terms, not to avoid all medical terms.
    • DThe passage states plain language helps those with limited literacy, not that they cannot learn.
  13. Question 13 of 25Easy

    Uses the passage before question 12.

    According to the passage, which of the following is a way nurses can apply plain language?

    1. A. Use long complex sentences.
    2. B. Speak quickly to save time.
    3. C. Avoid any written materials.
    4. D. Use short sentences and define technical terms.

    Show answer to question 13

    Answer: D. Use short sentences and define technical terms.

    The passage directly states that nurses should speak slowly, use short sentences, and define any necessary technical terms. This is a clear supporting detail.

    Why the other options are wrong

    • AThe passage advises using short sentences, not long complex ones.
    • BThe passage says to speak slowly, not quickly.
    • CThe passage encourages written materials at an appropriate reading level, not avoiding them.
  14. Question 14 of 25Medium

    Uses the passage before question 12.

    The passage suggests that using plain language in patient education is especially important for which group?

    1. A. Patients with advanced medical degrees.
    2. B. Patients with limited health literacy or English as a second language.
    3. C. Patients who are native English speakers with high literacy.
    4. D. Patients who prefer complex explanations.

    Show answer to question 14

    Answer: B. Patients with limited health literacy or English as a second language.

    The passage explicitly states that plain language can be especially helpful for patients with limited health literacy or those who speak English as a second language. This is an inference supported by the text.

    Why the other options are wrong

    • APatients with advanced medical degrees would likely understand jargon, so plain language is not especially important for them.
    • CWhile they may benefit, the passage highlights those with limited literacy or ESL as especially helped.
    • DThe passage does not mention such patients; plain language aims to simplify, not cater to complex preferences.
  15. Question 15 of 25Easy

    Uses the passage before question 12.

    In the context of the passage, the word 'jargon' most nearly means:

    1. A. Slang.
    2. B. Foreign language.
    3. C. Simple everyday words.
    4. D. Technical language used by professionals.

    Show answer to question 15

    Answer: D. Technical language used by professionals.

    The passage contrasts plain language with 'unnecessary medical jargon,' indicating that jargon refers to specialized terminology used by healthcare professionals. This is the correct meaning in context.

    Why the other options are wrong

    • ASlang is informal, nontechnical language, not the specialized terms implied by medical jargon.
    • BJargon can be in any language; the passage refers to specialized medical terms, not a foreign language.
    • CSimple everyday words are the opposite of jargon; plain language uses such words.
  16. Question 16 of 25Hard

    Passage

    Type 1 and Type 2 diabetes both result in persistent hyperglycemia, yet their underlying etiologies diverge significantly. In Type 1 diabetes, an autoimmune response selectively destroys pancreatic beta cells, causing an absolute deficiency of circulating insulin. In contrast, Type 2 diabetes primarily involves peripheral insulin resistance paired with progressive secretory dysfunction, meaning insulin is produced but target cells fail to respond effectively. Recognizing this distinction is vital for clinicians because it directly dictates therapeutic management: individuals with Type 1 require lifelong exogenous insulin replacement to survive, whereas those with Type 2 may initially achieve glycemic control through lifestyle modifications and oral hypoglycemic agents.

    In the passage, what does the phrase "this distinction" refer to?

    1. A. The disparity between lifestyle modifications and oral medications
    2. B. The difference in the underlying causes of Type 1 and Type 2 diabetes
    3. C. The destructive effect of autoimmune cells on peripheral target tissues
    4. D. The variance between hyperglycemia and normal blood glucose targets

    Show answer to question 16

    Answer: B. The difference in the underlying causes of Type 1 and Type 2 diabetes

    The phrase "this distinction" refers to the contrasting etiologies (underlying causes) of Type 1 and Type 2 diabetes detailed in the preceding two sentences. While therapeutic choices like insulin replacement and oral agents are discussed afterward, they represent the clinical consequences of understanding this fundamental pathological difference rather than the distinction itself.

  17. Question 17 of 25Easy

    Passage

    Regular physical activity is essential for maintaining cardiovascular health. Aerobic exercises, such as brisk walking, cycling, or swimming, increase the heart rate and strengthen the heart muscle. Studies show that consistent aerobic activity can lower blood pressure and improve cholesterol levels. Conversely, a sedentary lifestyle is linked to an increased risk of heart disease and obesity. Therefore, incorporating at least 150 minutes of moderate-intensity exercise into a weekly routine is highly recommended by health professionals.

    Which of the following statements is supported by the passage?

    1. A. High cholesterol is the only cause of heart disease.
    2. B. Swimming is the most effective form of aerobic exercise.
    3. C. Aerobic exercise must be performed for at least one hour daily.
    4. D. Sedentary lifestyles contribute to heart disease risk.

    Show answer to question 17

    Answer: D. Sedentary lifestyles contribute to heart disease risk.

    The text explicitly states that a sedentary lifestyle is linked to an increased risk of heart disease. While swimming is mentioned as an example of aerobic exercise, the passage does not claim it is the most effective method.

  18. Question 18 of 25Medium

    Passage

    As evening approaches and environmental light diminishes, the brain's pineal gland increases its synthesis and secretion of melatonin. Often called the hormone of darkness, melatonin acts not as a sedative that forces sleep, but rather as an internal biochemical signal indicating that biological night has arrived. This hormonal shift prepares the body for rest by encouraging a drop in core body temperature and modulating neural activity. However, extensive exposure to artificial blue light emitted by electronic screens can suppress melatonin production. This delay disrupts the natural circadian rhythm, making it substantially harder for individuals to achieve restful, timely slumber.

    Which of the following best captures the central idea as a title?

    1. A. Treatment Options for Chronic Insomnia and Sleep Disorders
    2. B. How Melatonin Regulates the Body's Sleep-Wake Cycle
    3. C. Thermoregulation During Human Rest and Wakefulness
    4. D. The Negative Impact of Evening Screen Time on Vision

    Show answer to question 18

    Answer: B. How Melatonin Regulates the Body's Sleep-Wake Cycle

    The passage describes how the hormone melatonin signals nighttime to prepare the body for sleep and how circadian alignment can be disrupted. The Negative Impact of Evening Screen Time on Vision is incorrect because the passage discusses blue light's effect on hormone suppression and sleep, not vision damage. Treatment Options for Chronic Insomnia and Sleep Disorders is too broad, as clinical treatments for insomnia are never addressed.

  19. Question 19 of 25Medium

    Passage

    Adequate systemic hydration is essential for preserving renal blood flow and maintaining metabolic balance. When fluid intake declines, the circulating blood volume decreases, which lowers arterial blood pressure and triggers specialized baroreceptors in the aortic arch and carotid sinuses. In response, the pituitary gland releases antidiuretic hormone into the bloodstream, directing the collecting ducts of the nephrons to reabsorb water back into circulation rather than excreting it. This physiological mechanism concentrates the urine and minimizes further water loss, but prolonged hypovolemia places severe strain on renal tubules, ultimately causing a sharp decline in glomerular filtration rate.

    According to the passage, what occurs when antidiuretic hormone acts upon the collecting ducts of the nephrons?

    1. A. Urine becomes diluted due to excess fluid excretion.
    2. B. Glomerular filtration rate increases to clear cellular waste.
    3. C. Water is reabsorbed into the bloodstream to conserve fluid.
    4. D. Arterial blood pressure drops rapidly within the aortic arch.

    Show answer to question 19

    Answer: C. Water is reabsorbed into the bloodstream to conserve fluid.

    The passage details that antidiuretic hormone directs the collecting ducts to reabsorb water back into circulation rather than excreting it. The passage notes that urine becomes concentrated rather than diluted, and blood pressure drops earlier in the process before the hormone is released.

  20. Question 20 of 25Medium

    Passage

    Recent studies on sleep hygiene suggest that the blue light emitted by smartphones can suppress the production of melatonin, the hormone responsible for regulating sleep cycles. As a result, individuals who use electronic devices late into the evening often experience difficulty falling asleep and poor sleep quality. Doctors recommend implementing a 'digital sunset' by turning off all screens at least one hour before bedtime to promote natural melatonin production and improve overall restfulness.

    Based on the passage, what can be predicted about an individual who begins using a smartphone immediately before going to sleep?

    1. A. They will experience an increase in melatonin production.
    2. B. They will achieve higher quality sleep due to alertness.
    3. C. They will likely face challenges in falling asleep.
    4. D. They will require less sleep than the average person.

    Show answer to question 20

    Answer: C. They will likely face challenges in falling asleep.

    The text explains that blue light suppresses melatonin, which makes it difficult to fall asleep. Therefore, using a phone right before bed would likely cause sleep onset issues. The text suggests blue light hinders sleep, making an increase in melatonin or higher quality sleep unlikely.

  21. Question 21 of 25Hard

    Passage

    The placebo effect occurs when a person experiences a real improvement in symptoms after receiving a treatment with no active therapeutic ingredient, such as a sugar pill. Researchers believe this happens partly because the brain's expectation of relief can trigger the release of natural chemicals that reduce pain or improve mood. This does not mean the original illness was imaginary; rather, it shows that psychological expectation can influence physical processes in measurable ways.

    What can be inferred from this passage about the placebo effect?

    1. A. Patients who respond to placebos were never actually experiencing real symptoms
    2. B. The brain can produce genuine physical changes based on what a person expects to happen
    3. C. Only patients with mild conditions are capable of experiencing a placebo response
    4. D. Sugar pills are equally effective as active medications for treating most illnesses

    Show answer to question 21

    Answer: B. The brain can produce genuine physical changes based on what a person expects to happen

    The passage says the brain's expectation of relief can trigger the release of natural chemicals that reduce pain or improve mood. Expectation can therefore produce real, measurable physical changes.

    Why the other options are wrong

    • AThe passage states explicitly that the original illness was not imaginary.
    • CThe passage never limits the placebo effect to mild conditions.
    • DThe passage does not compare sugar pills with active medications at all.
  22. Question 22 of 25Medium

    Passage

    Regular physical activity is vital for maintaining cardiovascular health. Studies consistently show that aerobic exercise reduces the risk of hypertension and stroke. Many fitness enthusiasts argue that high-intensity interval training (HIIT) is the most effective method for weight loss compared to steady-state cardio. While HIIT is efficient for burning calories in a short time, clinical guidelines suggest that a combination of aerobic and resistance training provides the most comprehensive health benefits for the general population.

    What is the author's primary purpose in this passage?

    1. A. To advocate for high-intensity interval training.
    2. B. To explain the physiological mechanics of stroke.
    3. C. To compare different types of exercise for health.
    4. D. To discourage people from performing steady-state cardio.

    Show answer to question 22

    Answer: C. To compare different types of exercise for health.

    The author discusses various forms of exercise, including HIIT and steady-state cardio, to explain their roles in cardiovascular health and general fitness. The passage does not take a side but rather presents different perspectives and guidelines.

  23. Question 23 of 25Hard

    Passage

    While many people view sleep as a passive state of rest, it is actually a highly active period for the brain. During deep sleep, the body undergoes significant repair processes, including tissue growth and muscle regeneration. Simultaneously, the brain processes information gathered during the day, consolidating memories and clearing out metabolic waste. This complex sequence of events is necessary for both physical recovery and cognitive function.

    What is the main idea of the passage?

    1. A. Metabolic waste is cleared during the night.
    2. B. Sleep is an active and essential biological process.
    3. C. Physical repair occurs during deep sleep stages.
    4. D. The brain processes memories during sleep.

    Show answer to question 23

    Answer: B. Sleep is an active and essential biological process.

    The passage argues against the idea that sleep is passive by highlighting the various active biological and cognitive processes occurring during rest. The other options are specific examples of the activity occurring during sleep.

  24. Question 24 of 25Hard

    Passage

    The infectious disease specialist emphasized that antibiotic stewardship is essential to attenuate the spread of multi-drug-resistant bacteria. Indiscriminate prescribing allows resistant strains to multiply freely, while targeted therapies weaken their evolutionary advantage. By reducing unnecessary usage, healthcare systems can diminish the selective pressure that fuels the emergence of superbugs and maintain effective treatment options.

    As used in the passage, what does the word 'attenuate' most nearly mean?

    1. A. To accelerate or hasten
    2. B. To eliminate entirely and permanently
    3. C. To reduce the strength or force of
    4. D. To document and catalog

    Show answer to question 24

    Answer: C. To reduce the strength or force of

    Contextual clues like weaken their evolutionary advantage and diminish the selective pressure demonstrate that attenuate means to reduce or weaken. To eliminate entirely and permanently is incorrect because the passage addresses managing and decreasing bacterial resistance rather than achieving absolute eradication.

  25. Question 25 of 25Hard

    Passage

    In the 19th century, many medical practices were based on the theory of 'miasma,' which suggested that diseases like cholera were caused by 'bad air' or rotting organic matter. This theory persisted until the development of Germ Theory, which proved that microorganisms, such as bacteria and viruses, are the actual cause of many infectious diseases. This shift in understanding revolutionized how doctors approached sterilization and hygiene in clinical settings.

    Which statement best describes the relationship between the miasma theory and Germ Theory as presented in the text?

    1. A. Germ Theory replaced the outdated miasma theory.
    2. B. Both theories were used to promote better hygiene.
    3. C. Miasma theory was proven correct by Germ Theory.
    4. D. Germ Theory was a subset of the miasma theory.

    Show answer to question 25

    Answer: A. Germ Theory replaced the outdated miasma theory.

    The passage describes a shift from the miasma theory to the Germ Theory, implying that the latter replaced the former once the cause of disease was understood. The text does not suggest they were part of the same theory or that they were used together for the same purpose.

The full HESI A2 bank has 836 Reading questions. See plans

Reading Comprehension is one of the seven common sections of the HESI A2 from Elsevier, and your nursing program decides whether you take it and sets the number of questions and the time. Below are 25 original Reading practice questions, each with the answer and an explanation.

Source: Elsevier HESI A2.

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Questions, answered

Are these actual HESI A2 questions?

No. They are original practice questions written from the public exam outline, not questions taken from the exam. Exam owners keep live questions confidential.

How many Reading questions are on the HESI A2?

It depends on your nursing program. Each program chooses the HESI A2 sections you take and sets the number of questions and the time, so ask your program which sections it requires. Source: Elsevier HESI A2.

Is this HESI A2 Reading practice test free?

Yes. The 25 questions on this page, with answers and explanations, are free to use, and there is no sign up. The full HESI A2 bank of 4,961 questions, with timed section tests and an AI tutor, comes with a plan.

How should I use this practice test?

Answer each question before you open Show answer, then read why the correct option is right and the others are not. Note the topics you miss and review them first. The HESI A2 study guide has 6 lessons for Reading, listed on this page.

These are original practice questions written from the public exam outline. They are not actual exam questions. HESI is a trademark of its owner. tests.global is not affiliated with or endorsed by Elsevier.

Updated November 1, 2026.