86,762 verified 4-option questions Double-checked by independent solution

ServSafe Manager · Hygiene and Health · 8 min read

Pathogens Spread by Food Handlers

In this lesson you will
  • Identify the Big Six foodborne pathogens and describe how infected food handlers transmit them to food, surfaces, and equipment.
  • Apply the FDA Food Code rules for regulatory notification, employee exclusion, employee restriction, and safe reinstatement.
  • Implement active managerial control procedures to prevent contamination from personal habits, wounds, and bodily fluid events.

The Big Six Pathogens and Managerial Reporting

Food service managers carry the primary responsibility for protecting guests from foodborne illness by maintaining active managerial control over staff hygiene and health. The FDA Food Code identifies six reportable pathogens commonly transmitted by food handlers, often referred to as the Big Six. These six biological hazards are Norovirus, Hepatitis A, Shigella spp., Shiga toxin-producing E. coli (STEC), Salmonella Typhi, and nontyphoidal Salmonella. Each of these organisms poses an exceptional threat in retail food operations because infected employees can easily spread them to ready-to-eat foods, clean utensils, and food-contact surfaces.

As a person in charge, you must establish clear employee health policies and know when an illness requires formal reporting. The FDA Food Code directs the person in charge to notify the regulatory authority when a food employee reports a diagnosis involving a Big Six pathogen. However, managers must recognize that state and local public health codes may have reporting and exclusion criteria that differ from the model FDA Food Code. Because state and local codes can vary depending on the jurisdiction, enforceable reporting requirements depend on the applicable state or local code, making it critical for managers to know their local rules.

When an employee tests positive for one of these organisms, managers must apply the FDA Food Code's pathogen-specific exclusion or restriction rules. An exclusion prohibits the employee from working in the food establishment entirely, while a restriction limits their activities so they do not work with exposed food, clean equipment, utensils, linens, or unwrapped single-service articles. Importantly, a diagnosis does not always require excluding an asymptomatic employee; rather, decisions depend strictly on the pathogen involved, the presence of symptoms, and whether the facility serves a highly susceptible population. Active managerial control means monitoring these staff reports daily and adjusting duties immediately to prevent widespread transmission.

For example, if a line cook mentions receiving a laboratory diagnosis for a Big Six pathogen but feels completely healthy, the manager cannot simply allow the cook to work as normal, nor should the manager immediately assume permanent termination is required. Instead, the manager reviews the specific pathogen rules under the local code, immediately notifies the regulatory authority, and places the employee on exclusion or restriction based on the standard criteria.

Exam tip. On the ServSafe exam, remember that receiving a medical diagnosis does not automatically mean every employee must be excluded from the building. Pay close attention to whether the worker has symptoms, what specific pathogen was diagnosed, and whether your establishment serves a highly susceptible population.

Common mistakes

  • Assuming that thorough cooking or reheating will make food safe after Staphylococcus aureus has grown and produced enterotoxins; the toxins are heat-stable and survive cooking.
  • Relying on alcohol-based hand sanitizers instead of mandatory soap and water handwashing during a suspected norovirus outbreak.
  • Believing that an employee diagnosed with a Big Six pathogen can only return to work with a doctor's written note; the FDA Food Code provides specific reinstatement criteria, and written medical clearance is not the only possible basis.
  • Applying the same blanket exclusion rule to all diagnosed employees without evaluating whether the person is asymptomatic, what pathogen is present, or whether the operation serves a highly susceptible population.

Key points

  • The FDA Food Code identifies six reportable Big Six pathogens: Norovirus, Hepatitis A, Shigella spp., STEC, Salmonella Typhi, and nontyphoidal Salmonella.
  • Managers must notify the regulatory authority when an employee reports a Big Six diagnosis, following applicable state or local public health codes.
  • Norovirus causes sudden vomiting and watery diarrhea, has an extremely low infectious dose, resists alcohol sanitizers, and requires written vomit and diarrhea cleanup procedures.
  • Hepatitis A causes jaundice and can be shed by infected workers weeks before symptoms appear; excluded workers require meeting specific reinstatement criteria and regulatory approval when required.
  • Salmonella Typhi lives exclusively in humans and requires immediate exclusion, whereas nontyphoidal Salmonella originates in animal reservoirs and may allow restriction for asymptomatic workers in general-public facilities.
  • Staphylococcus aureus produces heat-stable enterotoxins causing illness within 30 minutes to 8 hours; managers prevent it by eliminating bare-hand contact with ready-to-eat food, covering wounds with impermeable bandages and gloves, enforcing hair restraints, and monitoring handwashing.

Practice this section

Explained ServSafe Hygiene and Health questions, no account needed. ServSafe Hygiene and Health practice test

Study guide included with ServSafe plans

The full lesson continues with 3 more sections with exam tips, audio in English and Spanish, 5 Check yourself questions and 20 flashcards.

  • 1 month$38.99 $19.49
  • 3 months$113.99 $56.99
  • Lifetime$233.99 $116.99

One payment, no subscription.

See ServSafe plans

Already a member? Log in

Sample lesson: Handwashing, Hand Antiseptics and Hand Care

25 practice questions on this exam

Each ServSafe practice test has 25 original questions with the answers explained. No account needed.

Open the ServSafe practice tests
All ServSafe Manager lessons

Original lesson written for ServSafe Manager practice · updated October 15, 2026. Exam names are trademarks of their owners; tests.global is not affiliated with them.